Database Query Results : , , MLL2

MLL2, myeloid/lymphoid or mixed-lineage leukemia 2: Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
MLL2, also known as KMT2D (Lysine Methyltransferase 2D), is a gene that encodes a protein involved in the regulation of gene expression through histone methylation.
MLL2 is often referred to in the context of myeloid/lymphoid or mixed-lineage leukemia 2. The term "MLL" stands for "Mixed-Lineage Leukemia," and it refers to a family of genes, including MLL (KMT2A) and MLL2 (KMT2D).
MLL2 is often found to be mutated or downregulated in various cancers. These mutations can lead to a loss of function, which disrupts its role in histone methylation and gene regulation. This loss can contribute to oncogenesis by allowing the expression of oncogenes or silencing tumor suppressor genes.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: MLL2, myeloid/lymphoid or mixed-lineage leukemia 2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:194  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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