| Source: CGL-Driver Genes |
| Type: TSG |
| MSH6 is a gene that plays a crucial role in the DNA mismatch repair (MMR) system, which is responsible for correcting errors that occur during DNA replication. Mutations in the MSH6 gene can lead to a deficiency in this repair mechanism, resulting in an increased risk of certain types of cancer, particularly those associated with Lynch syndrome (also known as hereditary nonpolyposis colorectal cancer, or HNPCC). In many cancers associated with MSH6 mutations, there is often a loss of expression of the MSH6 protein. |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:208 State#:% Dir#:%
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