Database Query Results : , , PBRM1

PBRM1, polybromo 1: Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
PBRM1 (Polybromo 1) is a gene that encodes a protein involved in chromatin remodeling and regulation of gene expression. It is part of the PBAF (Polybromo-associated BAF) complex, which plays a crucial role in various cellular processes, including cell cycle regulation, differentiation, and response to DNA damage.
Mutations or alterations in the PBRM1 gene have been associated with several types of cancer, particularly renal cell carcinoma (RCC).

In many cases, reduced expression or functional loss is the dominant pattern rather than overexpression.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: PBRM1, polybromo 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:242  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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