Database Query Results : , , PGE1

PGE1, Prostaglandin E1: Click to Expand ⟱
Source:
Type:
Prostaglandin E1 (PGE1) is a type of prostaglandin, which is a group of lipid compounds that have various hormone-like effects in the body. PGE1 has been studied for its potential roles in various physiological processes, including inflammation, immune response, and vasodilation.

PGE1 is biochemically related to other prostaglandins that play prominent roles in cancer, current literature does not provide a clear picture of its regulation, prognostic associations, or definitive protumorigenic (or antitumorigenic) roles in cancer.


Scientific Papers found: Click to Expand⟱
2353- TQ,    The effects of thymoquinone on pancreatic cancer: Evidence from preclinical studies
- Review, PC, NA
BioAv↝, BioAv↑, MUC4↓, PKM2↓, eff↑, TumVol↓, HDAC↓, NF-kB↓, Bcl-2↓, Bcl-xL↓, survivin↓, XIAP↓, COX2↓, PGE1↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Mitochondria & Bioenergetics

XIAP↓, 1,  

Core Metabolism/Glycolysis

PKM2↓, 1,  

Cell Death

Bcl-2↓, 1,   Bcl-xL↓, 1,   survivin↓, 1,  

Proliferation, Differentiation & Cell State

HDAC↓, 1,  

Migration

MUC4↓, 1,  

Immune & Inflammatory Signaling

COX2↓, 1,   NF-kB↓, 1,   PGE1↓, 1,  

Drug Metabolism & Resistance

BioAv↑, 1,   BioAv↝, 1,   eff↑, 1,  

Functional Outcomes

TumVol↓, 1,  
Total Targets: 14

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: PGE1, Prostaglandin E1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:247  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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