| Source: CGL-Driver Genes |
| Type: TSG |
| BAP1 is the most frequently mutated deubiquitinase in human cancers and is a major tumor suppressor.BRCA-1 associated protein 1 (BAP1) is a tumor suppressor gene that has been implicated in the pathogenesis of several malignancies. Normal fibroblast cell cultures in individuals with heterozygous loss of BAP1 exhibited increased glycolysis and decreased aerobic mitochondrial respiration. |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:25 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid