| Source: CGL-Driver Genes |
| Type: TSG |
| PRDM1, also known as PR domain containing 1, with ZNF domain, is a gene that encodes a protein involved in various cellular processes, including differentiation, development, and immune response. PRDM1 has been studied for its dual role as a tumor suppressor and, in some cases, as an oncogene. PRDM1 is a critical transcription factor whose normal function is associated with cell differentiation and the shutdown of proliferative programs. In several B-cell malignancies, PRDM1 is frequently altered by mutations or reduced expression, and these changes are generally associated with a worse prognosis—supporting its role as a tumor suppressor. In other cancers, the patterns of expression and functional consequences appear more variable, underscoring the need for further research to fully understand its context-specific roles in tumorigenesis. |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:261 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid