Database Query Results : , , PTPN11

PTPN11, protein tyrosine phosphatase, non-receptor type 11; similar to protein tyrosine phosphatase, non-receptor type 11: Click to Expand ⟱
Source: CGL-Driver Genes
Type: Oncogene
PTPN11, also known as SHP-2, is a protein tyrosine phosphatase that plays a crucial role in various cellular processes, including cell growth, differentiation, and survival. It is involved in signaling pathways that are activated by growth factors and cytokines.

PTPN11 plays a pivotal role in mediating key growth and survival pathways. In many cancers—notably certain leukemias and subsets of solid tumors—activating mutations or overexpression of PTPN11 contribute to oncogenesis by amplifying downstream signals such as RAS/MAPK and PI3K/AKT. These alterations are generally associated with more aggressive tumor behavior and poorer outcomes, making PTPN11 both a prognostic marker and a target for emerging therapeutic interventions.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: PTPN11, protein tyrosine phosphatase, non-receptor type 11; similar to protein tyrosine phosphatase, non-receptor type 11
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

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