Database Query Results : , , SETBP1

SETBP1, SET binding protein 1: Click to Expand ⟱
Source: CGL-Driver Genes
Type: Oncogene
SETBP1 (SET binding protein 1) is a gene that encodes a protein involved in various cellular processes, including transcription regulation and cell signaling. Mutations in the SETBP1 gene have been associated with several types of cancer, particularly hematological malignancies.
In some cancers, particularly certain hematological malignancies like acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), SETBP1 may be overexpressed.
Scientific Papers found: Click to Expand⟱
1950- PL,    Increased Expression of FosB through Reactive Oxygen Species Accumulation Functions as Pro-Apoptotic Protein in Piperlongumine Treated MCF7 Breast Cancer Cells
- in-vitro, BC, MCF-7 - in-vitro, Lung, A549
selectivity↑, ROS↑, SETBP1↓, cl‑Casp9↑, eff↓, FOSB↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

Cell Death ⓘ

cl‑Casp9↑, 1,  

Transcription & Epigenetics ⓘ

SETBP1↓, 1,  

Migration ⓘ

FOSB↑, 1,  

Drug Metabolism & Resistance ⓘ

eff↓, 1,   selectivity↑, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: SETBP1, SET binding protein 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:279  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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