Database Query Results : , , SMARCA4

SMARCA4, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4: Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
SMARCA4, also known as BRG1, is a gene that encodes a protein involved in the SWI/SNF chromatin remodeling complex. This complex plays a crucial role in regulating gene expression by altering the structure of chromatin, making DNA more or less accessible for transcription.
SMARCA4 is considered a tumor suppressor gene. Loss of function mutations in SMARCA4 can lead to the disruption of normal chromatin remodeling, contributing to uncontrolled cell growth and tumorigenesis.
In many cancers, particularly those with mutations or deletions in the SMARCA4 gene, there is often a loss of expression of the SMARCA4 protein. This loss can lead to dysregulation of chromatin remodeling and contribute to tumorigenesis.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: SMARCA4, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:285  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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