| Source: CGL-Driver Genes |
| Type: Oncogene |
| SPOP (Speckle-type POZ protein) is a gene that encodes a protein involved in various cellular processes, including transcriptional regulation and protein degradation. SPOP mutations are most commonly associated with prostate cancer. In this context, SPOP is often found to be mutated rather than simply overexpressed or underexpressed. These mutations can lead to the loss of its normal function, which is to promote the degradation of certain proteins, including the androgen receptor. This dysregulation can contribute to the development and progression of prostate cancer. |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:290 State#:% Dir#:%
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