Database Query Results : , , TSHR

TSHR, thyroid stimulating hormone receptor: Click to Expand ⟱
Source: CGL-Driver Genes
Type: Oncogene
The thyroid-stimulating hormone receptor (TSHR) is a G protein-coupled receptor that plays a crucial role in regulating thyroid function by mediating the effects of thyroid-stimulating hormone (TSH) on the thyroid gland. TSHR is primarily involved in the synthesis and release of thyroid hormones.
The TSHR gene encodes the thyroid-stimulating hormone receptor (TSHR), which is a G protein-coupled receptor located on the surface of thyroid follicular cells. This receptor is crucial for the regulation of thyroid hormone synthesis and secretion in response to thyroid-stimulating hormone (TSH), which is produced by the pituitary gland.

TSHR expression is well established as a marker of differentiation and prognosis in thyroid cancer, with lower levels generally indicating a worse prognosis.

More aggressive thyroid cancers (poorly differentiated or anaplastic thyroid carcinoma) may show reduced or lost TSHR expression, which is associated with a worse prognosis.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: TSHR, thyroid stimulating hormone receptor
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:319  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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