Database Query Results : , , TumCM/A

TumCM/A, Tumor cell metabolism/acidosis: Click to Expand ⟱
Source: HalifaxProj(normalize)
Type:
Acidosis in the Tumor Microenvironment
Lactic Acidosis: The increased glycolytic activity in tumors leads to the accumulation of lactic acid, resulting in a lower pH in the tumor microenvironment. This lactic acidosis can have several effects on tumor behavior and the surrounding tissue.


Scientific Papers found: Click to Expand⟱
709- Bor,    Cellular changes in boric acid-treated DU-145 prostate cancer cells
- in-vitro, Pca, DU145
Cyc↓, MAPK↓, TumCMig↓, LAMP2↓, p‑ERK⇅, TumCM/A↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis

TumCM/A↑, 1,  

Cell Death

MAPK↓, 1,  

Autophagy & Lysosomes

LAMP2↓, 1,  

Cell Cycle & Senescence

Cyc↓, 1,  

Proliferation, Differentiation & Cell State

p‑ERK⇅, 1,  

Migration

TumCMig↓, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: TumCM/A, Tumor cell metabolism/acidosis
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:325  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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