| Source: CGL-Driver Genes |
| Type: Oncogene |
| U2 small nuclear RNA auxiliary factor 1 (U2AF1) is a protein that plays a crucial role in the splicing of pre-mRNA, which is an essential step in gene expression. It is part of the spliceosome complex, which is responsible for removing introns from pre-mRNA and joining exons together to form mature mRNA. Mutant U2AF1 contributes to a protumor phenotype by misregulating alternative splicing, potentially leading to the production of aberrant protein isoforms that disrupt normal cell differentiation and promote survival and proliferation. |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:331 State#:% Dir#:%
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