Database Query Results : , , CARD11

CARD11, caspase recruitment domain family, member 11: Click to Expand ⟱
Source: CGL-Driver Genes
Type: Oncogene
In normal B cells, antigen receptor-induced NF-kappaB activation requires CARD11, a cytoplasmic scaffolding protein.
CARD11 is a bona fide oncogenein DLBCL, providing a genetic rationale for the development of pharmacological inhibitors of the CARD11 pathway for DLBCL therapy.
Aberrant expression of CARD11 can promote cancer pathogenesis through changes to mTOR signaling and autophagy.


Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: CARD11, caspase recruitment domain family, member 11
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:39  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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