Database Query Results : , , BMD

BMD, bone mineral density: Click to Expand ⟱
Source:
Type:
The Bone Mineral Density (BMD) Test is a diagnostic tool used to measure the density and strength of bones. A bone mineral density (BMD) test measures calcium and other minerals in bone. Cancer treatments, including chemotherapy, hormone therapy, and radiation, can negatively impact bone health and lead to decreased BMD, increasing the risk of osteoporosis and fractures.
Some studies suggest that low BMD may be associated with poorer survival outcomes in certain cancer types, although the relationship can be complex and influenced by various factors.
Scientific Papers found: Click to Expand⟱
4542- AgNPs,    Silver Nanoparticles (AgNPs): Comprehensive Insights into Bio/Synthesis, Key Influencing Factors, Multifaceted Applications, and Toxicity─A 2024 Update
- Review, NA, NA
AntiCan↑, DNAdam↑, ATP↓, Apoptosis↑, ROS↓, TumCCA↑, *Bacteria↓, *BMD↑,
4081- betaCar,    Vitamin A supplementation and risk of skeletal fracture
- Study, NA, NA
BMD↓,
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑, *chemoPv↑,
3516- Bor,    Boron in wound healing: a comprehensive investigation of its diverse mechanisms
- Review, Wounds, NA
*Inflam↓, *antiOx↑, *ROS↓, *angioG↑, *COL1↑, *α-SMA↑, *TGF-β↑, *BMD↑, *hepatoP↑, *TNF-α↑, *HSP70/HSPA5↑, *SOD↑, *Catalase↑, *GSH↑, *MDA↓, *TOS↓, *IL6↓, *JAK2↓, *STAT3↓, *AMPK↑, *lipid-P↓, *VEGF↑, *Half-Life↝,
3512- Bor,    Activation of the EIF2α/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake
- in-vitro, Pca, DU145
TumCP↓, eIF2α↑, ATF4↑, ATF6↑, GADD34↑, CHOP↓, GRP78/BiP↑, GRP94↑, Risk↓, *BMD↑, Ca+2↓, *Half-Life↝, IRE1∅, chemoP↑,
3520- Bor,    Effect of boron element on photoaging in rats
- in-vivo, NA, NA
*hepatoP↑, *BMD↑, *COX2↓, *IL8↓, *NF-kB↓, *IL6↓, *TNF-α↓,
5065- dietSTF,  dietFMD,    Nutrition, GH/IGF-I Signaling, and Cancer
- Review, Var, NA
GH↓, IGF-1↓, glucose↓, IGFBP1↑, OS↑, Imm↑, neuroP↑, BMD↑, Dose↝, Risk↓, other↑, TumCP↓,
5055- Ex,    Why exercise has a crucial role in cancer prevention, risk reduction and improved outcomes
- Review, Var, NA
OS↑, IGF-1↓, IGFBP3↑, BRCA1↑, BRCA2↑, RAS↓, P53↑, HSPs↑, Leptin↓, Irisin↓, Resistin↓, NK cell↑, CRP↓, IL6↓, TNF-α↓, PGE1↓, COX2↓, *GSH↑, *Catalase↑, *SOD↑, *monoA↑, *EndoR↑, *testos↑, ROS↑, QoL↑, BMD↑, BowelM↑,
2153- Ex,    The Impact of Exercise on Cancer Mortality, Recurrence, and Treatment-Related Adverse Effects
- Review, Var, NA
eff↑, BMD↑, cognitive↑, OS↑, Remission↑, eff↑,
4005- K+,    Potassium
- Review, Nor, NA - Review, Stroke, NA
*Risk↓, *Dose↝, *Risk↓, *BMD↑, *glucose↓,
4705- MEL,    Melatonin: beyond circadian regulation - exploring its diverse physiological roles and therapeutic potential
- Review, Nor, NA
*CLOCK↝, *BMD↑, *cardioP↑, *neuroP↑, *Sleep↑,
2242- MF,    Electromagnetic stimulation increases mitochondrial function in osteogenic cells and promotes bone fracture repair
- in-vitro, Nor, NA
*MMP↑, *Diff↑, *OXPHOS↑, *BMD↑, ATP∅,
2238- MF,    Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects
- Review, Var, NA
*BMD↑, *VGCC↑, *Ca+2↑, *NO↑, *eff↓,
2240- MF,    Pulsed electromagnetic field induces Ca2+-dependent osteoblastogenesis in C3H10T1/2 mesenchymal cells through the Wnt-Ca2+/Wnt-β-catenin signaling pathway
- in-vitro, Nor, C3H10T1/2
*Ca+2↑, *Diff↑, *BMD↑, *Wnt↑, *β-catenin/ZEB1↑, *eff↝,
530- MF,    Low frequency sinusoidal electromagnetic fields promote the osteogenic differentiation of rat bone marrow mesenchymal stem cells by modulating miR-34b-5p/STAC2
- in-vivo, Nor, NA
*miR-34b-5p↓, *ALP↑, *RUNX2↑, *BMP2↑, *OCN↑, *OPN↑, *β-catenin/ZEB1↑, *STAC2↑, *Diff↑, *BMD↑,
4149- MF,    Pulsed Electro-Magnetic Field (PEMF) Effect on Bone Healing in Animal Models: A Review of Its Efficacy Related to Different Type of Damage
- Review, NA, NA
*other↑, *BDNF↑, *BMPs↑, *BMD↑,
3741- MF,    Promising application of Pulsed Electromagnetic Fields (PEMFs) in musculoskeletal disorders
- Review, NA, NA
*eff↑, *BMD↑, *Inflam↓, *PGE2↓, *IL6↓, *IL8↓, *NF-kB↓, *mTOR↝,
3471- MF,    The prevention effect of pulsed electromagnetic fields treatment on senile osteoporosis in vivo via improving the inflammatory bone microenvironment
- in-vivo, Nor, NA
*BMD↑, *NLRP3↓, *proCasp1↓, *cl‑Casp1↓, *IL1β↓, *GSDMD↓,
4349- MF,    Long-term effect of full-body pulsed electromagnetic field and exercise protocol in the treatment of men with osteopenia or osteoporosis: A randomized placebo-controlled trial
- Trial, ostP, NA
*BMD↑, *Pain↓, *QoL↑, *toxicity↓, *Dose↝, *Inflam↓,
4348- MF,    Pulsed electromagnetic field attenuates bone fragility in estrogen-deficient osteoporosis in rats
- in-vivo, ostP, NA
*BMD↑,
3535- MFrot,  MF,    Pulsed Electromagnetic Field Stimulation in Osteogenesis and Chondrogenesis: Signaling Pathways and Therapeutic Implications
- Review, Nor, NA
*eff↑, *COL2A1↑, *SOX9↑, *Ca+2↑, *FAK↑, *F-actin↑, *Inflam↓, *other↑, *Diff↑, *BMD↑,
2262- MFrot,  MF,    Effects of 0.4 T Rotating Magnetic Field Exposure on Density, Strength, Calcium and Metabolism of Rat Thigh Bones
- in-vivo, ostP, NA
*BMD↑, *eff↓, *ALP↑, *other↑,
193- MFrot,  MF,    Rotating Magnetic Field Mitigates Ankylosing Spondylitis Targeting Osteocytes and Chondrocytes via Ameliorating Immune Dysfunctions
- in-vivo, Arthritis, NA
BMD↑, Cartilage↑, IL17↓, IL22↓, IL23↓, IL28↓, CD4+↓, CD8+↓, LAMB3↑, COL4↓, THBS2↓, ITGA11↓, PPARγ↑, ACAA1↓, PLIN1↓, FABP4↓, PCK1↓, UCP1↓, TNF-α↓,
198- MFrot,  MF,    Biological effects of rotating magnetic field: A review from 1969 to 2021
- Review, Var, NA
AntiCan↑, breath↑, Pain↓, Appetite↑, Strength↑, BowelM↑, TumMeta↓, TumCCA↑, ETC↓, MMP↓, TumCD↑, selectivity↑, ROS↑, Casp3↑, TumCG↓, TumCCA↑, ChrMod↑, TumMeta↓, Imm↑, DCells↑, Akt↓, OS⇅, toxicity↓, QoL↑, hepatoP↑, Pain↓, Weight↑, Strength↑, Sleep↑, IL6↓, CD4+↑, CD8+↑, Ca+2↑, radioP↑, chemoP↑, *BMD↑, *AntiAge↑, *AMPK↑, *P21↓, *P53↓, *mTOR↓, *OS↑, *β-Endo↑, *5HT↓,
4128- Silicon,    Silicon as Versatile Player in Plant and Human Biology: Overlooked and Poorly Understood
- Review, NA, NA
*other↑, *BMD↑, *Dose↝, *cognitive↑, *Dose?,
2211- SK,    Shikonin mitigates ovariectomy-induced bone loss and RANKL-induced osteoclastogenesis via TRAF6-mediated signaling pathways
- in-vivo, ostP, NA
*BMD↑, *p‑NF-kB↓, *p‑p50↓, *p‑p65↓, *p‑ERK↓, *p‑cJun↓, *p‑p38↓,
2281- VitK2,    The biological responses of vitamin K2: A comprehensive review
- Review, Var, NA
*ROS↓, *12LOX↓, *NF-kB↓, *BMD↑, *hepatoP↑, cycD1/CCND1↓, PKCδ↓, STAT3↓, ERK↑, MAPK↓, ROS↑, PI3K↝, Akt↝, Hif1a↝, *neuroP↑,
1818- VitK2,    New insights on vitamin K biology with relevance to cancer
- Review, Var, NA
TumCG↓, ChemoSen↑, toxicity∅, OS↑, BMD↑, eff↑, MMP↓, ROS↑, eff↓, ERK↑, JNK↑, p38↑, Cyt‑c↑, Casp↑, ATP↓, lactateProd↑, AMPK↑, Rho↓, TumCG↓, BioAv↑, cardioP↑, Risk↓,
1815- VitK3,  VitK2,    Vitamin K
- Review, Nor, NA
*Dose↝, BMD↑,
1761- WBV,    Low Intensity Vibration Mitigates Tumor Progression and Protect Bone Quantity and Quality in a Murine Model of Myeloma
- in-vivo, Melanoma, NA
Dose∅, BMD↑, TumCI↓,
1754- WBV,    Vibration Therapy for Cancer-Related Bone Diseases
- Review, Var, NA
*BMD↑, *toxicity∅, other↓, Dose↝, Dose↑, eff↑, eff↑, eff↑,
1751- WBV,    Yoda1 Enhanced Low-Magnitude High-Frequency Vibration on Osteocytes in Regulation of MDA-MB-231 Breast Cancer Cell Migration
- in-vitro, BC, MDA-MB-231 - in-vitro, AML, RAW264.7
BMD↑, YAP/TEAD↑, TumCG↓, Strength↑, TumCI↓, Fas↑, Ca+2↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 32

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned ⓘ

Irisin↓, 1,   Leptin↓, 1,   Resistin↓, 1,  

Redox & Oxidative Stress ⓘ

ROS↓, 1,   ROS↑, 4,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 2,   ATP∅, 1,   ETC↓, 1,   MMP↓, 2,   UCP1↓, 1,  

Core Metabolism/Glycolysis ⓘ

ACAA1↓, 1,   AMPK↑, 1,   FABP4↓, 1,   glucose↓, 1,   lactateProd↑, 1,   PCK1↓, 1,   PLIN1↓, 1,   PPARγ↑, 1,  

Cell Death ⓘ

Akt↓, 1,   Akt↝, 1,   Apoptosis↑, 2,   Casp↑, 1,   Casp3↑, 1,   Cyt‑c↑, 1,   Fas↑, 1,   GADD34↑, 1,   JNK↑, 1,   MAPK↓, 1,   p38↑, 1,   TumCD↑, 1,   YAP/TEAD↑, 1,  

Transcription & Epigenetics ⓘ

BowelM↑, 2,   ChrMod↑, 1,   other↓, 1,   other↑, 1,  

Protein Folding & ER Stress ⓘ

ATF6↑, 1,   CHOP↓, 1,   eIF2α↑, 1,   GRP78/BiP↑, 1,   GRP94↑, 1,   HSPs↑, 1,   IRE1∅, 1,  

DNA Damage & Repair ⓘ

BRCA1↑, 1,   BRCA2↑, 1,   DNAdam↑, 1,   P53↑, 1,  

Cell Cycle & Senescence ⓘ

Cyc↓, 1,   cycD1/CCND1↓, 1,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State ⓘ

ERK↑, 2,   GH↓, 1,   HDAC↓, 1,   IGF-1↓, 3,   IGFBP1↑, 1,   IGFBP3↑, 1,   PI3K↝, 1,   RAS↓, 1,   STAT3↓, 1,   TumCG↓, 4,  

Migration ⓘ

Ca+2↓, 1,   Ca+2↑, 2,   Cartilage↑, 1,   COL4↓, 1,   ITGA11↓, 1,   LAMB3↑, 1,   PKCδ↓, 1,   Rho↓, 1,   THBS2↓, 1,   TumCI↓, 2,   TumCMig↓, 1,   TumCP↓, 2,   TumMeta↓, 2,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   ATF4↑, 1,   HIF-1↓, 1,   Hif1a↝, 1,  

Immune & Inflammatory Signaling ⓘ

CD4+↓, 1,   CD4+↑, 1,   COX2↓, 1,   CRP↓, 1,   DCells↑, 1,   IL17↓, 1,   IL22↓, 1,   IL23↓, 1,   IL28↓, 1,   IL6↓, 2,   Imm↑, 2,   NK cell↑, 1,   PGE1↓, 1,   PSA↓, 1,   TNF-α↓, 2,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   ChemoSen↑, 1,   Dose↑, 1,   Dose↝, 2,   Dose∅, 1,   eff↓, 1,   eff↑, 6,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

BMD↓, 1,   BMD↑, 8,   BRCA1↑, 1,   CRP↓, 1,   IL6↓, 2,   PSA↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 3,   Appetite↑, 1,   breath↑, 1,   cardioP↑, 1,   chemoP↑, 2,   cognitive↑, 1,   hepatoP↑, 1,   neuroP↑, 1,   OS↑, 4,   OS⇅, 1,   Pain↓, 2,   QoL↑, 2,   radioP↑, 1,   Remission↑, 1,   Risk↓, 4,   Sleep↑, 1,   Strength↑, 3,   toxicity↓, 1,   toxicity∅, 1,   TumVol↓, 1,   Weight↑, 1,  

Infection & Microbiome ⓘ

CD8+↓, 1,   CD8+↑, 1,  
Total Targets: 128

Pathway results for Effect on Normal Cells:


NA, unassigned ⓘ

EndoR↑, 1,  

Redox & Oxidative Stress ⓘ

antiOx↑, 1,   Catalase↑, 3,   GPx↑, 1,   GSH↑, 2,   lipid-P↓, 1,   MDA↓, 1,   OXPHOS↑, 1,   ROS↓, 2,   SAM-e↑, 1,   SOD↑, 3,   TOS↓, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↝, 1,   MMP↑, 1,  

Core Metabolism/Glycolysis ⓘ

12LOX↓, 1,   AMPK↑, 2,   glucose↓, 1,   NAD↝, 1,  

Cell Death ⓘ

BMP2↑, 1,   cl‑Casp1↓, 1,   proCasp1↓, 1,   GSDMD↓, 1,   p‑p38↓, 1,  

Kinase & Signal Transduction ⓘ

OCN↑, 1,   SOX9↑, 1,  

Transcription & Epigenetics ⓘ

p‑cJun↓, 1,   other↑, 4,  

Protein Folding & ER Stress ⓘ

HSP70/HSPA5↑, 1,  

DNA Damage & Repair ⓘ

P53↓, 1,  

Cell Cycle & Senescence ⓘ

P21↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

CLOCK↝, 1,   Diff↑, 4,   p‑ERK↓, 1,   mTOR↓, 1,   mTOR↝, 1,   RUNX2↑, 1,   STAT3↓, 1,   VGCC↑, 1,   Wnt↑, 1,  

Migration ⓘ

Ca+2↑, 3,   Ca+2↝, 1,   COL1↑, 1,   COL2A1↑, 1,   F-actin↑, 1,   FAK↑, 1,   OPN↑, 1,   serineP↓, 1,   STAC2↑, 1,   TGF-β↑, 1,   α-SMA↑, 1,   β-catenin/ZEB1↑, 2,   β-Endo↑, 1,  

Angiogenesis & Vasculature ⓘ

angioG↑, 1,   miR-34b-5p↓, 1,   NO↑, 1,   VEGF↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   IL1β↓, 1,   IL6↓, 3,   IL8↓, 2,   Inflam↓, 5,   JAK2↓, 1,   NF-kB↓, 3,   p‑NF-kB↓, 1,   p‑p50↓, 1,   p‑p65↓, 1,   PGE2↓, 1,   TNF-α↓, 2,   TNF-α↑, 1,   VitD↑, 1,  

Synaptic & Neurotransmission ⓘ

5HT↓, 1,   BDNF↑, 1,   monoA↑, 1,  

Protein Aggregation ⓘ

NLRP3↓, 1,  

Hormonal & Nuclear Receptors ⓘ

testos↑, 2,  

Drug Metabolism & Resistance ⓘ

Dose?, 1,   Dose↑, 1,   Dose↝, 5,   eff↓, 2,   eff↑, 3,   eff↝, 1,   Half-Life↝, 2,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

ALP↑, 2,   BMD↑, 23,   BMPs↑, 2,   Calcium↑, 1,   hs-CRP↓, 1,   IL6↓, 3,   Mag↑, 1,   VitD↑, 1,  

Functional Outcomes ⓘ

AntiAge↑, 1,   cardioP↑, 1,   chemoP↑, 1,   chemoPv↑, 1,   ChemoSideEff↓, 1,   cognitive↑, 2,   hepatoP↑, 3,   memory↑, 1,   neuroP↑, 3,   OS↑, 1,   Pain↓, 1,   QoL↑, 1,   Risk↓, 3,   Sleep↑, 1,   toxicity↓, 1,   toxicity∅, 1,  

Infection & Microbiome ⓘ

Bacteria↓, 1,  
Total Targets: 108

Scientific Paper Hit Count for: BMD, bone mineral density
13 Magnetic Fields
4 Boron
4 Magnetic Field Rotating
3 Vitamin K2
3 Whole Body Vibration
2 Exercise
1 Silver-NanoParticles
1 beta-carotene(VitA)
1 diet Short Term Fasting
1 diet FMD Fasting Mimicking Diet
1 Potassium
1 Melatonin
1 Silicic Acid
1 Shikonin
1 VitK3,menadione
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

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