Database Query Results : , , IL28

IL28, Interleukin-28: Click to Expand ⟱
Source:
Type:
Interleukin-28 (IL-28), also known as IL-28A or IL-28B, is a member of the type III interferon family, which also includes IL-29. These cytokines play a role in the immune response, particularly in antiviral defense and the regulation of immune cell activity. IL-28 is produced by various cell types, including macrophages, dendritic cells, and epithelial cells, in response to viral infections and other stimuli.
A cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses

IL-28 expression has been observed in various cancers, including hepatocellular carcinoma, colorectal cancer, and breast cancer. However, research on IL-28 in cancer is still relatively limited compared to other cytokines.
The expression of IL-28 can vary depending on the tumor type and the immune context, and it may be influenced by the presence of viral infections or inflammatory signals.

The prognostic significance of IL-28 in cancer is not yet fully established and may vary depending on the tumor type and the immune context.


Scientific Papers found: Click to Expand⟱
193- MFrot,  MF,    Rotating Magnetic Field Mitigates Ankylosing Spondylitis Targeting Osteocytes and Chondrocytes via Ameliorating Immune Dysfunctions
- in-vivo, Arthritis, NA
BMD↑, Cartilage↑, IL17↓, IL22↓, IL23↓, IL28↓, CD4+↓, CD8+↓, LAMB3↑, COL4↓, THBS2↓, ITGA11↓, PPARγ↑, ACAA1↓, PLIN1↓, FABP4↓, PCK1↓, UCP1↓, TNF-α↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Mitochondria & Bioenergetics ⓘ

UCP1↓, 1,  

Core Metabolism/Glycolysis ⓘ

ACAA1↓, 1,   FABP4↓, 1,   PCK1↓, 1,   PLIN1↓, 1,   PPARγ↑, 1,  

Migration ⓘ

Cartilage↑, 1,   COL4↓, 1,   ITGA11↓, 1,   LAMB3↑, 1,   THBS2↓, 1,  

Immune & Inflammatory Signaling ⓘ

CD4+↓, 1,   IL17↓, 1,   IL22↓, 1,   IL23↓, 1,   IL28↓, 1,   TNF-α↓, 1,  

Clinical Biomarkers ⓘ

BMD↑, 1,  

Infection & Microbiome ⓘ

CD8+↓, 1,  
Total Targets: 19

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: IL28, Interleukin-28
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:542  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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