Database Query Results : , , DCells

DCells, dendritic Cells: Click to Expand ⟱
Source:
Type:
Dendritic cells (DCs) are central regulators of the adaptive immune response, and as such are necessary for T cell-mediated cancer immunity.
DC subsets are often classified by developmental origin as conventional DC [including type 1 conventional DC (cDC1) and type 2 conventional DC (cDC2)], monocyte-derived DC (MoDC), plasmacytoid DC (pDC) as well as the emerging appreciation of a population, termed DC3.

Dendritic cells play a vital role in the immune response to cancer, and their presence and functional status in the tumor microenvironment can significantly impact prognosis. Generally, a higher density of activated dendritic cells is associated with better clinical outcomes across various cancer types.
Scientific Papers found: Click to Expand⟱
1601- Cu,    The copper (II) complex of salicylate phenanthroline induces immunogenic cell death of colorectal cancer cells through inducing endoplasmic reticulum stress
- in-vitro, CRC, NA
i-CRT↓, ICD↑, i-ATP↓, i-HMGB1↓, ER Stress↑, ROS↑, DCells↑, CD8+↑, IL12↑, IFN-γ↑, TGF-β↓,
1034- CUR,  immuno,    Enhanced anti‐tumor effects of the PD‐1 blockade combined with a highly absorptive form of curcumin targeting STAT3
- in-vivo, NA, NA
DCells↑, T-Cell↑,
220- MFrot,  MF,    Effect of low frequency magnetic fields on melanoma: tumor inhibition and immune modulation
- in-vitro, Melanoma, B16-F10
OS↑, DCells↑, T-Cell↑, Apoptosis↑, IL1↑, IFN-γ↓, IL10↑, TumCG↓, ROS↑,
221- MFrot,  MF,    Low Frequency Magnetic Fields Enhance Antitumor Immune Response against Mouse H22 Hepatocellular Carcinoma
- in-vivo, Liver, NA
OS↑, TumCG↓, IL6↓, GM-CSF↓, CXCc↓, Macrophages↑, DCells↑, CD4+↑, CD8+↑, IL12↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ICD↑, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics ⓘ

i-ATP↓, 1,  

Cell Death ⓘ

Apoptosis↑, 1,  

Protein Folding & ER Stress ⓘ

i-CRT↓, 1,   ER Stress↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

TumCG↓, 2,  

Migration ⓘ

TGF-β↓, 1,  

Immune & Inflammatory Signaling ⓘ

CD4+↑, 1,   CXCc↓, 1,   DCells↑, 4,   GM-CSF↓, 1,   i-HMGB1↓, 1,   IFN-γ↓, 1,   IFN-γ↑, 1,   IL1↑, 1,   IL10↑, 1,   IL12↑, 2,   IL6↓, 1,   Macrophages↑, 1,   T-Cell↑, 2,  

Clinical Biomarkers ⓘ

IL6↓, 1,  

Functional Outcomes ⓘ

OS↑, 2,  

Infection & Microbiome ⓘ

CD8+↑, 2,  
Total Targets: 24

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: DCells, dendritic Cells
2 Magnetic Field Rotating
2 Magnetic Fields
1 Copper and Cu NanoParticlex
1 Curcumin
1 immunotherapy
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:572  State#:%  Dir#:%
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