Database Query Results : , , NFAM1

NFAM1, Neural Factor Activating Mast cells 1: Click to Expand ⟱
Source:
Type:
NFAM1 (Neural Factor Activating Mast cells 1) is a protein that interacts with ITAM1 (Immunoreceptor Tyrosine-based Activation Motif 1). NFAM1 is a member of the Fc receptor gamma chain (FcRγ) family, which is a group of proteins that play a crucial role in the activation of immune cells, such as mast cells and basophils.
NFAM1 has been shown to be overexpressed in breast cancer tissues, particularly in triple-negative breast cancer (TNBC) and HER2-positive breast cancer, non-small cell lung cancer (NSCLC), Leukemia, and Melanoma.
• Immune evasion: NFAM1 may help cancer cells evade the immune response by inhibiting the activation of immune cells, such as T cells and natural killer cells.
• Cell proliferation and survival: NFAM1 may promote cell proliferation and survival by activating signaling pathways that regulate cell growth and survival.
• Angiogenesis: NFAM1 may promote angiogenesis, the formation of new blood vessels, which is essential for tumor growth and metastasis.
Scientific Papers found: Click to Expand⟱
232- AL,    A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans
- Human, Nor, NA
*AhR↑, *ARNT↑, *Hif1a↑, *Jun↑, *NFAT↑, *NFAM1↑, *REL↑, *OSM↑, *NFAT↑, *CXCc↑, *IL2↑, *IL6↑, *LIF↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Cell Death ⓘ

AhR↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

Jun↑, 1,  

Migration ⓘ

NFAM1↑, 1,   NFAT↑, 2,  

Angiogenesis & Vasculature ⓘ

Hif1a↑, 1,   REL↑, 1,  

Immune & Inflammatory Signaling ⓘ

CXCc↑, 1,   IL2↑, 1,   IL6↑, 1,   LIF↑, 1,   OSM↑, 1,  

Hormonal & Nuclear Receptors ⓘ

ARNT↑, 1,  

Clinical Biomarkers ⓘ

IL6↑, 1,  
Total Targets: 13

Scientific Paper Hit Count for: NFAM1, Neural Factor Activating Mast cells 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:587  State#:%  Dir#:%
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