Database Query Results : , , ACC-α

ACC-α, Acetyl-CoA Carboxylase alpha: Click to Expand ⟱
Source:
Type:
An enzyme that plays a crucial role in the regulation of fatty acid synthesis. Research has shown that ACC-α is overexpressed in various types of cancer, including breast, lung, and colon cancer.
Scientific Papers found: Click to Expand⟱
445- CUR,    Curcumin Regulates the Progression of Colorectal Cancer via LncRNA NBR2/AMPK Pathway
- in-vitro, CRC, HCT116 - in-vitro, CRC, HCT8 - in-vitro, CRC, SW480 - in-vitro, CRC, SW-620
p‑AMPK↑, p‑ACC-α↑, NBR2↑, p‑S6K↓, mTOR↓,
293- HCA,  Tam,    Hydroxycitric acid potentiates the cytotoxic effect of tamoxifen in MCF-7 breast cancer cells through inhibition of ATP citrate lyase
- in-vitro, BC, MCF-7
TumCG↓, Apoptosis↑, ACLY↓, ACC-α↓, Fas↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

ACC-α↓, 1,   p‑ACC-α↑, 1,   ACLY↓, 1,   p‑AMPK↑, 1,   p‑S6K↓, 1,  

Cell Death ⓘ

Apoptosis↑, 1,   Fas↓, 1,  

DNA Damage & Repair ⓘ

NBR2↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

mTOR↓, 1,   TumCG↓, 1,  
Total Targets: 10

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: ACC-α, Acetyl-CoA Carboxylase alpha
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:605  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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