Database Query Results : , , MMP11

MMP11, matrix metalloproteinase 11: Click to Expand ⟱
Source:
Type:
A type of enzyme that plays a role in the breakdown of the extracellular matrix, a network of proteins and other molecules that provide structural support to cells and tissues.
MMP11 is overexpressed in various types of cancer, including breast, lung, colon, and prostate cancer. High levels of MMP11 have been associated with poor prognosis and reduced survival in cancer patients.
Scientific Papers found: Click to Expand⟱
299- ALA,  Cisplatin,  PacT,    Anti-cancer effects of alpha lipoic acid, cisplatin and paclitaxel combination in the OVCAR-3 ovarian adenocarcinoma cell line
- in-vitro, Ovarian, OVCAR-3
MMP9↓, MMP11↓, MAPK↓,
4382- SNP,    Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism
- in-vitro, Nor, RAW264.7
*GSH↓, *NO↑, *TNF-α↑, *MMP3↑, *MMP11↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

MAPK↓, 1,  

Migration ⓘ

MMP11↓, 1,   MMP9↓, 1,  
Total Targets: 3

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

GSH↓, 1,  

Migration ⓘ

MMP11↑, 1,   MMP3↑, 1,  

Angiogenesis & Vasculature ⓘ

NO↑, 1,  

Immune & Inflammatory Signaling ⓘ

TNF-α↑, 1,  
Total Targets: 5

Scientific Paper Hit Count for: MMP11, matrix metalloproteinase 11
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:608  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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