Database Query Results : , , MRGPRF

MRGPRF, Mas-related G-protein coupled receptor, member F: Click to Expand ⟱
Source:
Type:
MRGPRF (Mas-related G-protein coupled receptor, member F) is a receptor that has been implicated in various physiological and pathological processes, including cancer.

Research has shown that MRGPRF is overexpressed in certain types of cancer, such as breast, lung, and colon cancer. The receptor is thought to play a role in promoting tumor growth and metastasis by regulating various signaling pathways involved in cell proliferation, survival, and migration.

Some studies have suggested that MRGPRF may be a potential therapeutic target for cancer treatment. For example, blocking MRGPRF with specific antagonists has been shown to inhibit tumor growth and reduce metastasis in preclinical models of cancer.
Scientific Papers found: Click to Expand⟱
432- CUR,    Curcumin-Induced Global Profiling of Transcriptomes in Small Cell Lung Cancer Cells
- in-vitro, Lung, H446
Bcl-2↓, cycF↓, LOX1↓, VEGF↓, MRGPRF↓, BAX↑, Cyt‑c↑, miR-548ah-5p↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

BAX↑, 1,   Bcl-2↓, 1,   Cyt‑c↑, 1,   miR-548ah-5p↑, 1,  

Cell Cycle & Senescence ⓘ

cycF↓, 1,  

Migration ⓘ

MRGPRF↓, 1,  

Angiogenesis & Vasculature ⓘ

LOX1↓, 1,   VEGF↓, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: MRGPRF, Mas-related G-protein coupled receptor, member F
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:681  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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