Database Query Results : , , KCNQ1OT1

KCNQ1OT1, KCNQ1OT1: Click to Expand ⟱
Source:
Type: long non-coding RNA (lncRNA)
KCNQ1OT1 is a long non-coding RNA (lncRNA) that has been implicated in various types of cancer. It is located on chromosome 11p15.5, a region that is often associated with cancer and other diseases.

KCNQ1OT1 is overexpressed in several types of cancer, including:
HCC, Colorectal cancer, Breast, Lung, Ovarian.
Scientific Papers found: Click to Expand⟱
444- CUR,  Cisplatin,    LncRNA KCNQ1OT1 is a key factor in the reversal effect of curcumin on cisplatin resistance in the colorectal cancer cells
- vitro+vivo, CRC, HCT8
TumVol↓, Apoptosis↑, Bcl-2↓, Cyt‑c↑, BAX↑, cl‑Casp3↑, cl‑PARP1↑, miR-497↑, KCNQ1OT1↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

Apoptosis↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   cl‑Casp3↑, 1,   Cyt‑c↑, 1,   miR-497↑, 1,  

Transcription & Epigenetics ⓘ

KCNQ1OT1↓, 1,  

DNA Damage & Repair ⓘ

cl‑PARP1↑, 1,  

Functional Outcomes ⓘ

TumVol↓, 1,  
Total Targets: 9

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: KCNQ1OT1, KCNQ1OT1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:702  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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