Database Query Results : , , RPS6KA1

RPS6KA1, ribosomal protein S6 kinase alpha-1: Click to Expand ⟱
Source:
Type: gene
RPS6KA1 is a gene that encodes a protein called ribosomal protein S6 kinase alpha-1. This protein is involved in various cellular processes, including cell growth, proliferation, and survival.

Research has shown that RPS6KA1 is overexpressed in several types of cancer, including breast, lung, and colon cancer.
Scientific Papers found: Click to Expand⟱
452- CUR,    Curcumin downregulates the PI3K-AKT-mTOR pathway and inhibits growth and progression in head and neck cancer cells
- vitro+vivo, HNSCC, SCC9 - vitro+vivo, HNSCC, FaDu - vitro+vivo, HNSCC, HaCaT
TumCCA↑, PI3k/Akt/mTOR↓, Casp3↑, EGFR↓, EGF↑, PRKCG↑, p‑Akt↓, p‑mTOR↓, RPS6KA1↓, EIF4E↓, proCasp3↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Mitochondria & Bioenergetics ⓘ

EGF↑, 1,  

Core Metabolism/Glycolysis ⓘ

PI3k/Akt/mTOR↓, 1,  

Cell Death ⓘ

p‑Akt↓, 1,   Casp3↑, 1,   proCasp3↓, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

EIF4E↓, 1,   p‑mTOR↓, 1,   PRKCG↑, 1,   RPS6KA1↓, 1,  

Angiogenesis & Vasculature ⓘ

EGFR↓, 1,  

Clinical Biomarkers ⓘ

EGFR↓, 1,  
Total Targets: 12

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: RPS6KA1, ribosomal protein S6 kinase alpha-1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:715  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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