Database Query Results : , , miR-210

miR-210, miR-210: Click to Expand ⟱
Source:
Type: hypoxia-inducible miRNA
miR-210 is a hypoxia-inducible miRNA, meaning that its expression is increased in response to low oxygen levels (hypoxia), which is a common feature of the tumor microenvironment.
miR-210 has been found to be overexpressed in various types of cancer, including breast, lung, colon, and pancreatic cancer. This overexpression has been associated with cancer progression, metastasis, and poor prognosis.
Scientific Papers found: Click to Expand⟱
692- EGCG,    EGCG: The antioxidant powerhouse in lung cancer management and chemotherapy enhancement
- Review, NA, NA
ROS↑, Apoptosis↑, DNAdam↑, CTR1↑, JWA↑, β-catenin/ZEB1↓, P53↑, Vim↓, VEGF↓, p‑Akt↓, Hif1a↓, COX2↓, ERK↓, NF-kB↓, Akt↓, Bcl-xL↓, miR-210↓,
670- EGCG,    Epigallocatechin-3-gallate and its nanoformulation in cervical cancer therapy: the role of genes, MicroRNA and DNA methylation patterns
- Review, NA, NA
TumCCA↑, P53↑, ERK↓, EGFR↓, p‑ERK↑, VEGF↓, Hif1a↓, miR-203↓, miR-210↑,
522- MF,    Low Magnetic Field Exposure Alters Prostate Cancer Cell Properties
- in-vitro, Pca, PC3
MMP2↑, MMP9↑, miR-21↑, miR-155↑, miR-210↑, miR-200c↓, miR-126↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

Cell Death ⓘ

Akt↓, 1,   p‑Akt↓, 1,   Apoptosis↑, 1,   Bcl-xL↓, 1,   JWA↑, 1,  

Transcription & Epigenetics ⓘ

miR-21↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,   P53↑, 2,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↓, 2,   p‑ERK↑, 1,  

Migration ⓘ

miR-155↑, 1,   miR-200c↓, 1,   miR-203↓, 1,   MMP2↑, 1,   MMP9↑, 1,   Vim↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

EGFR↓, 1,   Hif1a↓, 2,   miR-126↓, 1,   miR-210↓, 1,   miR-210↑, 2,   VEGF↓, 2,  

Barriers & Transport ⓘ

CTR1↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   NF-kB↓, 1,  

Clinical Biomarkers ⓘ

EGFR↓, 1,  
Total Targets: 29

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-210, miR-210
2 EGCG (Epigallocatechin Gallate)
1 Magnetic Fields
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:764  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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