Database Query Results : , , ACSS2

ACSS2, Acyl-CoA Synthetase Short Chain Family Member 2: Click to Expand ⟱
Source:
Type:
ACSS2 (Acyl-CoA Synthetase Short Chain Family Member 2) is an enzyme that plays a crucial role in the metabolism of fatty acids.
ACSS enzymes (mainly ACSS1 in mitochondria and ACSS2 in the cytosol and nucleus) convert acetate into acetyl‐CoA.
ACSS2 is overexpressed in: breast, lung, CRC, prostate, pancreatic, GBM, ovarian, liver, Esophageal cancers.

-Upregulation of ACSS2 has been observed in various cancers, where it enables cancer cells to maintain acetyl‐CoA levels for Lipid synthesis needed for membrane biogenesis.
Scientific Papers found: Click to Expand⟱
549- AL,    Allicin, a naturally occurring antibiotic from garlic, specifically inhibits acetyl-CoA synthetase
ACSS2↓,
2557- AL,    Allicin, a naturally occurring antibiotic from garlic, specifically inhibits acetyl-CoA synthetase
- in-vitro, NA, NA
ACSS2↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

ACSS2↓, 2,  
Total Targets: 1

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: ACSS2, Acyl-CoA Synthetase Short Chain Family Member 2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:786  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page