Database Query Results : , , LysoPr

LysoPr, lysosomal proteolysis: Click to Expand ⟱
Source:
Type:
Lysosomal proteolysis is a cellular process that involves the degradation of proteins within lysosomes, which are membrane-bound organelles that contain digestive enzymes.

Lysosomal proteolysis is generally considered protumorigenic. The degradation of extracellular matrix components and the release of proteolytic enzymes can facilitate tumor cell invasion and metastasis. Additionally, lysosomal proteolysis can contribute to the activation of signaling pathways that promote cell survival and proliferation.
Scientific Papers found: Click to Expand⟱
558- ART/DHA,    Artemisinin and Its Synthetic Derivatives as a Possible Therapy for Cancer
- Review, NA, NA
ROS↑, oncosis↑, Apoptosis↑, LysoPr↑, TumAuto↑, Wnt/(β-catenin)↑, AMP↓, NF-kB↓, Myc↓, CREBBP↓, mTOR↓, E-cadherin↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

Core Metabolism/Glycolysis ⓘ

AMP↓, 1,  

Cell Death ⓘ

Apoptosis↑, 1,   Myc↓, 1,   oncosis↑, 1,  

Autophagy & Lysosomes ⓘ

TumAuto↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

CREBBP↓, 1,   mTOR↓, 1,   Wnt/(β-catenin)↑, 1,  

Migration ⓘ

E-cadherin↑, 1,   LysoPr↑, 1,  

Immune & Inflammatory Signaling ⓘ

NF-kB↓, 1,  

Clinical Biomarkers ⓘ

Myc↓, 1,  
Total Targets: 13

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: LysoPr, lysosomal proteolysis
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:793  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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