Database Query Results : , , serineP

serineP, serine protease: Click to Expand ⟱
Source:
Type:
Serine proteases are a family of enzymes that play a crucial role in various cellular processes, including cell growth, differentiation, and survival.
Role of serine proteases in cancer:
-Tumor growth and angiogenesis: Serine proteases, such as urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor-1 (PAI-1), are involved in the regulation of tumor growth and angiogenesis.
-Invasion and metastasis: Serine proteases, such as (MMPs) and cathepsins, are involved in the degradation of the extracellular matrix, facilitating tumor cell invasion and metastasis.
Scientific Papers found: Click to Expand⟱
3518- Bor,    Boron Report
- Review, Var, NA - Review, AD, NA
Risk↓, serineP↓, PSA↓, TumVol↓, IGF-1↓, *Mag↑, *Calcium↑, *VitD↑, *COX2↓, *5LO↓, *PGE2↓, *NF-kB↓, *cognitive↑,
697- Bor,    Boron-containing compounds as preventive and chemotherapeutic agents for cancer
- Review, NA, NA
serineP↓, NADHdeh↓, Apoptosis↑,
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑, *chemoPv↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

NADHdeh↓, 1,  

Cell Death ⓘ

Apoptosis↑, 2,  

Cell Cycle & Senescence ⓘ

Cyc↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

HDAC↓, 1,   IGF-1↓, 2,  

Migration ⓘ

serineP↓, 2,   TumCMig↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   HIF-1↓, 1,  

Immune & Inflammatory Signaling ⓘ

PSA↓, 2,  

Clinical Biomarkers ⓘ

PSA↓, 2,  

Functional Outcomes ⓘ

AntiCan↑, 1,   Risk↓, 2,   TumVol↓, 2,  
Total Targets: 14

Pathway results for Effect on Normal Cells:


NA, unassigned ⓘ

chemoPv↑, 1,  

Redox & Oxidative Stress ⓘ

Catalase↑, 1,   GPx↑, 1,   SAM-e↑, 1,   SOD↑, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↝, 1,  

Core Metabolism/Glycolysis ⓘ

NAD↝, 1,  

Migration ⓘ

5LO↓, 1,   Ca+2↝, 1,   serineP↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   Inflam↓, 1,   NF-kB↓, 1,   PGE2↓, 1,   TNF-α↓, 1,   VitD↑, 2,  

Hormonal & Nuclear Receptors ⓘ

testos↑, 1,  

Drug Metabolism & Resistance ⓘ

Dose↑, 1,   Dose↝, 1,   eff↑, 1,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

BMD↑, 1,   BMPs↑, 1,   Calcium↑, 2,   hs-CRP↓, 1,   Mag↑, 2,   VitD↑, 2,  

Functional Outcomes ⓘ

chemoP↑, 1,   ChemoSideEff↓, 1,   cognitive↑, 2,   memory↑, 1,   neuroP↑, 1,   Risk↓, 1,  
Total Targets: 33

Scientific Paper Hit Count for: serineP, serine protease
3 Boron
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:850  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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