Database Query Results : , , PCBP1

PCBP1, Poly(rC) Binding Protein 1: Click to Expand ⟱
Source:
Type:
PCBP1 (Poly(rC) Binding Protein 1) is a protein that plays a crucial role in the regulation of gene expression, particularly in the context of cancer.
PCBP1 has been shown to promote tumor growth, invasion, and metastasis by regulating the expression of genes involved in cell proliferation, survival, and migration.
PCBP1 has been found to be highly expressed in cancer stem cells, which are thought to be responsible for cancer initiation, progression, and recurrence.
Scientific Papers found: Click to Expand⟱
739- Bor,    Borax regulates iron chaperone- and autophagy-mediated ferroptosis pathway in glioblastoma cells
- in-vitro, GBM, U87MG - in-vitro, Nor, HMC3
TumCG↓, TumCP↓, TumCCA↑, PCBP1↓, GSH↓, GPx4↓, Beclin-1↑, MDA↑, ACSL4↑, Casp3↑, Casp7↑, Ferroptosis↑, *toxicity↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↑, 1,   GPx4↓, 1,   GSH↓, 1,   MDA↑, 1,  

Core Metabolism/Glycolysis ⓘ

ACSL4↑, 1,  

Cell Death ⓘ

Casp3↑, 1,   Casp7↑, 1,   Ferroptosis↑, 1,  

Autophagy & Lysosomes ⓘ

Beclin-1↑, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

TumCG↓, 1,  

Migration ⓘ

PCBP1↓, 1,   TumCP↓, 1,  
Total Targets: 13

Pathway results for Effect on Normal Cells:


Functional Outcomes ⓘ

toxicity↓, 1,  
Total Targets: 1

Scientific Paper Hit Count for: PCBP1, Poly(rC) Binding Protein 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:866  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page