Database Query Results : , , GNLY

GNLY, Granulysin: Click to Expand ⟱
Source:
Type: Granulysin
Granulysin is a Granulysin that is expressed by cytotoxic T cells and natural killer cells, and plays a crucial role in the immune system's ability to eliminate infected cells and tumor cells.
Scientific Papers found: Click to Expand⟱
741- Bor,    Boron Derivatives Inhibit the Proliferation of Breast Cancer Cells and Affect Tumor-Specific T Cell Activity In Vitro by Distinct Mechanisms
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
MOB1↓, PD-L1↑, p‑YAP/TEAD↝, IFN-γ↓, sFasL↑, Perforin↓, GranA↓, GranB↓, GNLY↓, PD-1↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

GranA↓, 1,   GranB↓, 1,   Perforin↓, 1,   sFasL↑, 1,   p‑YAP/TEAD↝, 1,  

Migration ⓘ

MOB1↓, 1,  

Immune & Inflammatory Signaling ⓘ

GNLY↓, 1,   IFN-γ↓, 1,   PD-1↑, 1,   PD-L1↑, 1,  

Clinical Biomarkers ⓘ

PD-L1↑, 1,  
Total Targets: 11

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: GNLY, Granulysin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:873  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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