Database Query Results : , , TNF-β
TNF-β, Tumor Necrosis Factor-beta: Click to Expand ⟱
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Tumor Necrosis Factor-beta (TNF-β), also known as Lymphotoxin-alpha (LT-α), is a cytokine involved in systemic inflammation and one of the cytokines that make up the tumor necrosis factor family.
TNF-β is typically high expression in cancers with poor prognosis.
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Scientific Papers found: Click to Expand⟱
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in-vitro, |
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NA |
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in-vivo, |
NA, |
NA |
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TumCP↓, Apoptosis↑, Bcl-2↓, BAX↑, IL10↓, TNF-β↓,
*hepatoP↑, *neuroP↑, *ROS↓, *β-Amyloid↓, *Inflam↓, *Aβ↓, *NF-kB↓, *TNF-α↓, *TNF-β↓, *iNOS↓, *NO↓, *COX2↓,
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2
Pathway results for Effect on Cancer / Diseased Cells:
Cell Death ⓘ
Apoptosis↑, 1, BAX↑, 1, Bcl-2↓, 1,
Migration ⓘ
TumCP↓, 1,
Immune & Inflammatory Signaling ⓘ
IL10↓, 1, TNF-β↓, 1,
Total Targets: 6
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
ROS↓, 1,
Cell Death ⓘ
iNOS↓, 1,
Angiogenesis & Vasculature ⓘ
NO↓, 1,
Immune & Inflammatory Signaling ⓘ
COX2↓, 1, Inflam↓, 1, NF-kB↓, 1, TNF-α↓, 1, TNF-β↓, 1,
Protein Aggregation ⓘ
Aβ↓, 1, β-Amyloid↓, 1,
Functional Outcomes ⓘ
hepatoP↑, 1, neuroP↑, 1,
Total Targets: 12
Scientific Paper Hit Count for: TNF-β, Tumor Necrosis Factor-beta
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:914 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid
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