Database Query Results : , , ENO2

ENO2, Enolase 2: Click to Expand ⟱

Source:

Type:

ENO2 (Enolase 2) is an enzyme that plays a crucial role in the glycolytic pathway, which is often upregulated in cancer cells, and related to poor prognosis.
ENO2 (Enolase 2) is a cytoplasmic enzyme that plays a crucial role in the glycolytic pathway, as I mentioned earlier. It is a key enzyme in the conversion of 2-phosphoglycerate to enolpyruvate, which is then converted to pyruvate.

ENOX2 (Enox2), on the other hand, is a cell surface enzyme that is also known as Cytosolic Enolase 2 or ENO2 variant. ENOX2 is a truncated form of ENO2 that lacks the first 96 amino acids of the full-length ENO2 protein. Despite this difference, ENOX2 retains enolase activity and is also involved in the glycolytic pathway.

Scientific Papers found: Click to Expand⟱

933-

CUR,

EP,

Effective electrochemotherapy with curcumin in MDA-MB-231-human, triple negative breast cancer cells: A global proteomics study

in-vitro,

BC,

50uM, 1200v/c,100us

Apoptosis↑, ALDOA↓, ENO2↓, LDHA↓, LDHB↓, PFKP↓, PGK1↓, PGM1↓, PGAM1↓, OXPHOS↑, TCA↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

OXPHOS↑, 1,

Core Metabolism/Glycolysis ⓘ

ALDOA↓, 1, ENO2↓, 1, LDHA↓, 1, LDHB↓, 1, PFKP↓, 1, PGAM1↓, 1, PGK1↓, 1, PGM1↓, 1, TCA↑, 1,

Cell Death ⓘ

Apoptosis↑, 1,
Total Targets: 11

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: ENO2, Enolase 2

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells