Database Query Results : , , CarnA

CarnA, Carnitine Acyltransferase: Click to Expand ⟱
Source:
Type:
(Carnitine Acyltransferase) is an enzyme that plays a crucial role in the metabolism of fatty acids. In the context of cancer, CAT expression has been studied in various types of tumors.
(Carnitine Acyltransferase) is typically upregulated in various types of cancer. Studies have shown that CAT expression is increased in many types of cancer, including breast, colorectal, prostate, lung, liver, pancreatic, and glioblastoma, among others.
High expression is linked to poor prognosis.

Carnitine acyltransferases” is an umbrella term covering a family of enzymes involved in the transport and metabolism of acyl‐groups (typically long‐chain fatty acids) by conjugation with carnitine. The key members include:
CPT1 (Carnitine Palmitoyltransferase 1) -frequently upregulated in cancer
CPT2 (Carnitine Palmitoyltransferase 2)
CACT (Carnitine Acylcarnitine Translocase)
CrAT (Carnitine Acetyltransferase

Many studies have shown that enzymes facilitating fatty acid oxidation (especially CPT1A) can be upregulated in cancers that rely on fatty acid oxidation to boost their energy production and support biosynthesis. This upregulation is an adaptation to increased energy demands and altered nutrient availability.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: CarnA, Carnitine Acyltransferase
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:941  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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