Database Query Results : , , lact/pyru

lact/pyru, lactate/pyruvate ratio: Click to Expand ⟱
Source:
Type:
The lactate/pyruvate ratio is a measure of the balance between lactate and pyruvate, two key metabolites involved in cellular energy metabolism. In cancer, the lactate/pyruvate ratio is often increased, which is often associated with poor prognosis.
Scientific Papers found: Click to Expand⟱
996- Ba,  Tam,    Baicalein resensitizes tamoxifen‐resistant breast cancer cells by reducing aerobic glycolysis and reversing mitochondrial dysfunction via inhibition of hypoxia‐inducible factor‐1α
Hif1a↓, Glycolysis↓, GlucoseCon↓, lactateProd↓, lact/pyru↓, ROS↑, Apoptosis↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

Core Metabolism/Glycolysis ⓘ

GlucoseCon↓, 1,   Glycolysis↓, 1,   lact/pyru↓, 1,   lactateProd↓, 1,  

Cell Death ⓘ

Apoptosis↑, 1,  

Angiogenesis & Vasculature ⓘ

Hif1a↓, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: lact/pyru, lactate/pyruvate ratio
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:950  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page