Database Query Results : , , miR-133a-3p

miR-133a-3p, miR-133a-3p: Click to Expand ⟱
Source:
Type:
miR-133a-3p is a microRNA that has been implicated in various types of cancer.
Tumor-Suppressive microRNA, Lineage Control, and Metastasis Restraint

Downregulated in:Esophageal ,GC,BC,Lung,Ovarina (low expression=poor prognoisis).

Upregulated in: HCC, RCC (associated with good prognosis).
Scientific Papers found: Click to Expand⟱
1027- AS,    Astragalus polysaccharide (APS) attenuated PD-L1-mediated immunosuppression via the miR-133a-3p/MSN axis in HCC
- vitro+vivo, HCC, SMMC-7721 cell
PD-L1↓, miR-133a-3p↝,
5027- QC,    NRF2 Is Targeted By the Polyphenol Quercetin and Induces Apoptosis, in Part, through up Regulation of Pro Apoptotic Mirs
- in-vivo, AML, NA
HDAC4↓, NRF2↓, p‑NRF2↓, miR-133a-3p↑, miR-206↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

NRF2↓, 1,   p‑NRF2↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

HDAC4↓, 1,  

Migration ⓘ

miR-133a-3p↑, 1,   miR-133a-3p↝, 1,   miR-206↑, 1,  

Immune & Inflammatory Signaling ⓘ

PD-L1↓, 1,  

Clinical Biomarkers ⓘ

PD-L1↓, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-133a-3p, miR-133a-3p
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:972  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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