Sutherlandioside D / TumCG Cancer Research Results

SuD, Sutherlandioside D: Click to Expand ⟱

Features:

Extract of Sutherlandia frutescens is a medicinal plant. S. frutescens commonly known as the “cancer bush” by South African healers.

TumCG, Tumor cell growth: Click to Expand ⟱

Source:

Type:

Normal cells grow and divide in a regulated manner through the cell cycle, which consists of phases (G1, S, G2, and M).
Cancer cells often bypass these regulatory mechanisms, leading to uncontrolled proliferation. This can result from mutations in genes that control the cell cycle, such as oncogenes (which promote cell division) and tumor suppressor genes (which inhibit cell division).

Scientific Papers found: Click to Expand⟱

112-

SuD,

Inhibition of Gli/hedgehog signaling in prostate cancer cells by “cancer bush” Sutherlandia frutescens extract

in-vitro,

Pca,

PC3

 167 ug/mL

in-vitro,

Pca,

LNCaP

HH↓, Gli1↓, PTCH1↓, TumCG↓, chemoPv↑, eff↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Proliferation, Differentiation & Cell State ⓘ

Gli1↓, 1, HH↓, 1, PTCH1↓, 1, TumCG↓, 1,

Drug Metabolism & Resistance ⓘ

eff↑, 1,

Functional Outcomes ⓘ

chemoPv↑, 1,
Total Targets: 6

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: TumCG, Tumor cell growth

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells