Radiotherapy/Radiation / HATs Cancer Research Results
Rad, Radiotherapy/Radiation: Click to Expand ⟱
| Features: |
Treatment of disease with radiation, especially by selective irradiation with x-rays or other ionizing radiation and by ingestion of radioisotopes.
Radiosensitizer
Atorvaqone, (mitochondria inhibitor) decrease O2 consumption making more O2 available as a radiosensitizer.
|
HATs, histone acetyltransferases: Click to Expand ⟱
| Source: |
| Type: |
Histone acetyltransferases (HATs) are a family of enzymes that play a crucial role in the regulation of gene expression by modifying chromatin structure. HATs transfer acetyl groups to the lysine residues of histone proteins, which are the main components of chromatin. This modification, known as histone acetylation, leads to the relaxation of chromatin structure, allowing for increased access of transcription factors to DNA and promoting gene expression.
HATs is overexpressed in cancers with poor prognosis.
|
Scientific Papers found: Click to Expand⟱
| - |
in-vitro, |
Lung, |
A549 |
|
|
|
- |
in-vitro, |
NA, |
HeLa |
|
|
|
HATs↓, other↑,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Transcription & Epigenetics ⓘ
HATs↓, 1, other↑, 1,
Total Targets: 2
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: HATs, histone acetyltransferases
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:201 Target#:886 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid
Home Page