Cytosine Arabinoside/Cytarabine Cancer Research Results

Ara-C, Cytosine Arabinoside/Cytarabine: Click to Expand ⟱
Features: Chemotherapy Drug

Cytarabine - Cytosine Arabinoside

Recommended Abbreviation: Ara-C, Cytarabine

Alternative Names: Cytosine arabinoside, Ara-C

Type: Antimetabolite / pyrimidine nucleoside analog / chemotherapy drug

Function: Cytarabine is converted intracellularly to its active triphosphate metabolite, ara-CTP, which competes with deoxycytidine triphosphate for incorporation into DNA and inhibits DNA polymerase. This disrupts DNA synthesis and preferentially affects rapidly dividing cells during S phase.

Cancer: Established anticancer drug used particularly in acute myeloid leukemia and other hematologic malignancies. Cytarabine induces replication stress, DNA synthesis inhibition, cell-cycle arrest, and apoptosis.
Scientific Papers found: Click to Expand⟱
Showing Research Papers: 0 to 0 of 0

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:471  Target#:%  State#:%  Dir#:%
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