Tanshinone IIA Cancer Research Results

Tan IIA, Tanshinone IIA: Click to Expand ⟱
Features:

Tanshinone IIA

Recommended Abbreviation: Tan IIA

Alternative Names: Tanshinone 2A, Tanshinone II A

Type: Natural product / diterpene quinone / tanshinone

Source: Major lipophilic bioactive constituent of the roots and rhizomes of Salvia miltiorrhiza Bunge (Danshen).

Function: Tanshinone IIA has antioxidant, anti-inflammatory, neuroprotective, cardiovascular, metabolic, and anticancer activities. It modulates multiple signaling pathways involved in apoptosis, autophagy, proliferation, angiogenesis, inflammation, oxidative stress, and cellular metabolism.

Cancer: Tanshinone IIA has extensive preclinical anticancer activity across multiple tumor types. Reported effects include proliferation ↓, migration/invasion ↓, angiogenesis ↓, apoptosis ↑, autophagy modulation, and suppression of oncogenic signaling including PI3K/AKT, MAPK, JAK/STAT3, and related pathways.

Alzheimer's Disease: Tanshinone IIA has demonstrated neuroprotective and experimental anti-Alzheimer activity, including antioxidant and anti-inflammatory effects, protection against neuronal injury, and modulation of pathways associated with amyloid and neurodegenerative stress. Clinical evidence for Alzheimer's disease remains limited.
Scientific Papers found: Click to Expand⟱
Showing Research Papers: 0 to 0 of 0

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:478  Target#:%  State#:%  Dir#:%
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