Database Query Results : , , GS3Kβ

GS3Kβ, Glycogen Synthase Kinase 3 Beta: Click to Expand ⟱
Source:
Type:
GSK3β is a serine/threonine kinase involved in numerous cellular processes including glycogen metabolism, cell cycle regulation, and apoptosis.
It is a key regulator in several pathways such as Wnt/β-catenin, PI3K/AKT, and NF-κB, which are central to oncogenic processes and tumor progression.

Glycogen Synthase Kinase 3 Beta (GSK3β) is a critical kinase involved in diverse cellular processes that govern tumor cell survival, proliferation, and apoptosis. Its expression and activity are frequently altered in cancer, with both overactivation and inhibition linked to adverse outcomes, depending on the cellular context and specific signaling environment.
Scientific Papers found: Click to Expand⟱
1335- AS,    Extract from Astragalus membranaceus inhibit breast cancer cells proliferation via PI3K/AKT/mTOR signaling pathway
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, SkBr3
p‑PI3K↓, p‑GS3Kβ↓, p‑Akt↓, p‑mTOR↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

p‑GS3Kβ↓, 1,  

Cell Death ⓘ

p‑Akt↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

p‑mTOR↓, 1,   p‑PI3K↓, 1,  
Total Targets: 4

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: GS3Kβ, Glycogen Synthase Kinase 3 Beta
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1065  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page