KeyT Cancer Research Results

KeyT, Keytones: Click to Expand ⟱
Source:
Type:
A ketogenic diet is high in fats and low in carbohydrates, which shifts the body’s metabolism to produce ketone bodies (such as β-hydroxybutyrate and acetoacetate) as an alternative energy source.
The three main ketone bodies are:
-Beta-hydroxybutyrate (BHB): The most abundant and commonly measured ketone in the blood.
-Acetoacetate: Can be measured in both the blood and urine.
-Acetone: Often measured in the breath; it is a byproduct of acetoacetate breakdown.

1. Blood Ketone Meters (accurate, fast)
-Nutritional ketosis is often defined by BHB levels between 0.5 to 3.0 mmol/L.
2. Urine Ketone Strips (urine test may not accurately reflect blood levels)
3. Breath Ketone Analyzers(not always perfectly correlate with blood BHB concentrations.)
Scientific Papers found: Click to Expand⟱
1810- dietKeto,  Oxy,    The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer
- in-vivo, Var, NA
BG↓, TumCG↓, OS↑, eff↑, Dose∅, KeyT↑, eff↑, cachexia↓, ChemoSen↑, *ROS↓, ROS↑, lipid-P↑, selectivity↑, toxicity∅,
7483- H2,  Cisplatin,    Molecular hydrogen attenuates cisplatin-induced nephrotoxicity by modulating β-hydroxybutyrate metabolism
- in-vivo, Nor, HK-2
RenoP↑, BHB↑, HMGCS2↑, chemoP↑, *IL2↓, *IL6↓, *MCP1/CCL2↓, *TNF-α↓, *KeyT↝, *Inflam↓, *ROS↓, *MMP↑, *ATP↑, *MFN2↑, *PGC-1α↑, *BUN↓, *creat↓,
8110- L-Orn,    L-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism
- Trial, Nor, NA
*Dose↝, *KeyT↝, *FFA/NEFA↝, *NH3↓, *fatigue↓,
2644- MCT,    The Effects of Medium-Chain Triglyceride Oil Supplementation on Endurance Performance and Substrate Utilization in Healthy Populations: A Systematic Review
- Review, Nor, NA
*KeyT↑, *Dose↝, eff↑,
3902- MCT,    Effects of Caprylic Triglyceride on Cognitive Performance and Cerebral Glucose Metabolism in Mild Alzheimer’s Disease: A Single-Case Observation
- Case Report, AD, NA
*cognitive↑, *KeyT↑,
3903- MCT,    Retrospective case studies of the efficacy of caprylic triglyceride in mild-to-moderate Alzheimer’s disease
- Case Report, AD, NA
*KeyT↑, *cognitive↑, *eff↑,
3904- MCT,    Retrospective cohort study of the efficacy of caprylic triglyceride in patients with mild-to-moderate alzheimer’s disease
- Human, AD, NA
*memory↑, *cognitive↑, *KeyT↑,
3905- MCT,    Medium Chain Triglycerides induce mild ketosis and may improve cognition in Alzheimer's disease. A systematic review and meta-analysis of human studies
- Review, AD, NA
*cognitive↑, *KeyT↑, *eff↑, *other↑, *toxicity↓,

Showing Research Papers: 1 to 8 of 8

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

BHB↑, 1,   HMGCS2↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

lipid-P↑, 1,   ROS↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

KeyT↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCG↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 1,   Dose∅, 1,   eff↑, 3,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

BG↓, 1,  

Functional Outcomes(tgid=23) ⓘ

cachexia↓, 1,   chemoP↑, 1,   OS↑, 1,   RenoP↑, 1,   toxicity∅, 1,  
Total Targets: 16

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

FFA/NEFA↝, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

MFN2↑, 1,   ROS↓, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   MMP↑, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

BUN↓, 1,   KeyT↑, 5,   KeyT↝, 2,   NH3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL2↓, 1,   IL6↓, 1,   Inflam↓, 1,   MCP1/CCL2↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 2,   eff↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

creat↓, 1,   IL6↓, 1,  

Functional Outcomes(tgid=23) ⓘ

cognitive↑, 4,   fatigue↓, 1,   memory↑, 1,   toxicity↓, 1,  
Total Targets: 24

Scientific Paper Hit Count for: KeyT, Keytones
5 MCToil
1 diet Ketogenic
1 Oxygen, Hyperbaric
1 Hydrogen Gas
1 Cisplatin
1 L-ornithine
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1187  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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