Database Query Results : , , SGLTs

SGLTs, Sodium-Glucose Cotransporters: Click to Expand ⟱
Source:
Type:
Sodium-Glucose Cotransporters (SGLTs) primarily functions in the uptake of glucose in a sodium-dependent manner—distinct from the facilitative glucose transporters (GLUTs).
• SGLTs (notably SGLT1 and SGLT2) facilitate active glucose uptake, which is especially important in tissues where glucose levels are low or where rapid uptake is needed.

– Some studies have observed overexpression of SGLT1 in certain tumor types, including pancreatic, prostate, and colorectal cancers.
– SGLT1 expression in tumors may correlate with aggressive growth behavior as it supports increased glucose uptake in environments where GLUT activity might be insufficient.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: SGLTs, Sodium-Glucose Cotransporters
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1200  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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