Database Query Results : , , GATA3

GATA3, GATA binding protein 3: Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
GATA3 is often considered a key player in breast cancer biology. It is frequently expressed in luminal subtype breast cancers and is associated with a better prognosis.
GATA3 acts as a tumor suppressor. Its expression can inhibit the proliferation of cancer cells and promote differentiation, which is often lost in cancerous cells.
GATA3 is known to regulate the expression of estrogen receptors (ER), which are critical in the development and progression of ER-positive breast cancers.

GATA3 is an important transcription factor with varying roles in different cancers. In breast cancer, it is generally associated with a favorable prognosis, while its role in other cancers can be more complex.


Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: GATA3, GATA binding protein 3
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:123  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page