Database Query Results : , , GNA11/Gαq

GNA11/Gαq, guanine nucleotide binding protein (G protein), alpha 11 (Gq class): Click to Expand ⟱
Source: CGL-Driver Genes
Type: Oncogene
Guanine nucleotide-binding proteins, commonly known as G proteins, play a crucial role in cellular signaling pathways. The Gq class of G proteins, which includes the alpha subunit Gαq, is involved in various physiological processes, including the regulation of phospholipase C (PLC) activity, leading to the production of inositol trisphosphate (IP3) and diacylglycerol (DAG). These second messengers are important for calcium signaling and activating protein kGαq signaling can promote cell proliferation and survival through various pathways, including the activation of the MAPK/ERK pathway. Dysregulation of these pathways can lead to uncontrolled cell growth, a hallmark of cancer.
inase C (PKC), which can influence cell growth, differentiation, and survival.

GNA11 expression and its associated signaling pathways are often altered in various cancers, and these changes can be linked to poorer prognosis due to their role in promoting tumor growth and survival.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: GNA11/Gαq, guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:130  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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