Database Query Results : , , sonoP

sonoP, sonoporation: Click to Expand ⟱
Source:
Type:
Sonoporation is a technique that uses ultrasound waves to transiently increase the permeability of cell membranes, allowing for the enhanced delivery of drugs, genes, or other therapeutic agents into cells.

-Microbubbles (gas-filled contrast agents commonly used in ultrasound imaging) are often administered alongside the therapeutic agent. When exposed to ultrasound, these microbubbles oscillate and can collapse (a process known as cavitation). This cavitation enhances the permeability of nearby cell membranes, thus facilitating drug or gene uptake.
Scientific Papers found: Click to Expand⟱
2548- SDT,    Sonoporation, a Novel Frontier for Cancer Treatment: A Review of the Literature
- Review, Var, NA
sonoP↑, Dose↝, eff↓, Dose↝, BioEnh↑, toxicity↝,
2549- SDT,    Landscape of Cellular Bioeffects Triggered by Ultrasound-Induced Sonoporation
- Review, Var, NA
sonoP↑, tumCV↓, MMP↓, ROS↑, Ca+2↑, eff↝, eff↑, selectivity↑, Half-Life↝, Dose↝, P-gp↓, ER Stress↑, other↑,
2550- SDT,    Intracellular Delivery and Calcium Transients Generated in Sonoporation Facilitated by Microbubbles
- in-vitro, Nor, NA
*Ca+2↑, sonoP↑, BioEnh↑,
2551- SDT,    Sonoporation: Past, Present, and Future
- Review, Var, NA
other↝, sonoP↑, Dose↝,
2539- SNP,  SDT,    Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780
- in-vitro, Melanoma, A2780S
tumCV↓, sonoP↑, BioEnh↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 1,  

Transcription & Epigenetics ⓘ

other↑, 1,   other↝, 1,   tumCV↓, 2,  

Protein Folding & ER Stress ⓘ

ER Stress↑, 1,  

Migration ⓘ

Ca+2↑, 1,  

Barriers & Transport ⓘ

P-gp↓, 1,   sonoP↑, 5,  

Drug Metabolism & Resistance ⓘ

BioEnh↑, 3,   Dose↝, 4,   eff↓, 1,   eff↑, 1,   eff↝, 1,   Half-Life↝, 1,   selectivity↑, 1,  

Functional Outcomes ⓘ

toxicity↝, 1,  
Total Targets: 17

Pathway results for Effect on Normal Cells:


Migration ⓘ

Ca+2↑, 1,  
Total Targets: 1

Scientific Paper Hit Count for: sonoP, sonoporation
5 SonoDynamic Therapy UltraSound
1 Silver-NanoParticles
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1318  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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