Database Query Results : , , GNAS

GNAS, GNAS complex locus: Click to Expand ⟱
Source: CGL-Driver Genes
Type: Oncogene
The GNAS complex locus is a genomic region located on chromosome 20 that encodes the GNAS gene, which is responsible for producing the Gs alpha subunit of the G protein involved in various signaling pathways, particularly those related to hormone signaling and cell growth.
Activating mutations in the GNAS gene can lead to constitutive activation of signaling pathways, which may promote cell proliferation and survival. These mutations are often found in certain types of tumors, including pituitary adenomas and some thyroid cancers.

GNAS expression and mutations are associated with various cancers, particularly pituitary adenomas and some thyroid and colorectal cancers. The presence of GNAS mutations can influence tumor behavior and may be linked to poorer outcomes in certain contexts.


Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: GNAS, GNAS complex locus
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:132  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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