Database Query Results : , , monoA

monoA, monoamines: Click to Expand ⟱
Source:
Type:
Monoamines are neurotransmitters that include dopamine (DA), serotonin (5-HT), norepinephrine (NE), epinephrine (E), and histamine. They play critical roles in mood regulation, cognition, and autonomic functions.
-Decreased serotonin levels are observed in Alzheimer’s Disease AD brains.
Scientific Papers found: Click to Expand⟱
3627- Croc,    The effects of Crocus sativus (saffron) and its constituents on nervous system: A review
- Review, AD, NA - Review, Stroke, NA
*other↑, *monoA↑, *Aβ↓, *AChE↓, *cognitive↑, *neuroP↑, *lipid-P↓, *SOD↑, *ROS↓, *GPx↑, *MDA↓, *memory↑, *antiOx↑, *Inflam↓, *other↓, *ER Stress↓,
3619- RosA,    Rosmarinic acid suppresses Alzheimer’s disease development by reducing amyloid β aggregation by increasing monoamine secretion
- Review, AD, NA
*BioAv↓, *BBB↝, *monoA↑, *TGF-β↓, *Aβ↓,
4858- Uro,    The Metabolite Urolithin-A Ameliorates Oxidative Stress in Neuro-2a Cells, Becoming a Potential Neuroprotective Agent
- in-vitro, Nor, NA
*ROS?, *neuroP↑, *lipid-P↓, *Catalase↑, *SOD↑, *GPx↑, *GSR↑, *monoA↓, *tyrosinase↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   Catalase↑, 1,   GPx↑, 2,   GSR↑, 1,   lipid-P↓, 2,   MDA↓, 1,   ROS?, 1,   ROS↓, 1,   SOD↑, 2,  

Transcription & Epigenetics ⓘ

other↓, 1,   other↑, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

tyrosinase↓, 1,  

Migration ⓘ

TGF-β↓, 1,  

Barriers & Transport ⓘ

BBB↝, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1,  

Synaptic & Neurotransmission ⓘ

AChE↓, 1,   monoA↓, 1,   monoA↑, 2,  

Protein Aggregation ⓘ

Aβ↓, 2,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,  

Functional Outcomes ⓘ

cognitive↑, 1,   memory↑, 1,   neuroP↑, 2,  
Total Targets: 24

Scientific Paper Hit Count for: monoA, monoamines
1 Crocetin
1 Rosmarinic acid
1 Urolithin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1350  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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