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| INR (International Normalized Ratio) is a standardized measure of blood coagulation derived from the prothrombin time (PT). It reflects the activity of the extrinsic coagulation pathway, which depends on liver-synthesized clotting factors (II, VII, IX, X). It is a host/organ-function biomarker. | Elevated INR Usually Means | Clinical Interpretation | | ---------------------------------- | --------------------------------------------------- | | Reduced hepatic synthetic function | Liver involvement, cirrhosis, or treatment toxicity | | Vitamin K deficiency | Malnutrition, cholestasis, antibiotics | | Consumptive coagulopathy | Advanced cancer, sepsis | | Anticoagulant effect | Warfarin or drug interactions | In cancer, rising INR often signals systemic decline, not just a lab abnormality. |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1413 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid