Database Query Results : , , TRPV6
TRPV6, Transient Receptor Potential Vanilloid 6: Click to Expand ⟱
| Source: |
| Type: biomarker |
TRPV6<.b> is a highly Ca²⁺-selective plasma membrane ion channel best known for epithelial calcium absorption. In cancer, TRPV6 is frequently overexpressed and repurposed as a pro-proliferative, pro-survival signaling conduit, making it a calcium-oncogenic driver rather than a passive transporter.
TRPV6 is markedly upregulated in several cancers:
-Prostate cancer (one of the strongest associations)
-Breast cancer
-Ovarian cancer
-Pancreatic cancer
-Colon cancer
High TRPV6 expression correlates with:
-Aggressive disease
-High proliferation
-Poor prognosis
Biomarker: TRPV6 overexpression indicates Ca²⁺-driven proliferation
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Scientific Papers found: Click to Expand⟱
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0
Pathway results for Effect on Cancer / Diseased Cells:
Total Targets: 0
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: TRPV6, Transient Receptor Potential Vanilloid 6
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1443 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid
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