Database Query Results : , , HIST1H3B

HIST1H3B, histone cluster 1, H3j, H3, H3h, H3g, H3f1, H3e, H3d, H3c, H3b, H3a, H2ad; histone cluster 2, H3a, H3c, H3d: Click to Expand ⟱
Source: CGL-Driver Genes
Type: Oncogene
A gene that encodes a variant of histone H3, which is a protein that plays a crucial role in the structure and function of chromatin in eukaryotic cells. Histones are involved in the packaging of DNA into a compact, organized structure, allowing for proper gene regulation and expression. mutations in histone genes, including HIST1H3B, can be found in certain cancers, such as pediatric gliomas and other tumors. These mutations can lead to changes in the epigenetic landscape of the cells, contributing to tumorigenesis by affecting how genes are turned on or off.
Expression levels of histone genes, including HIST1H3B, can be upregulated or downregulated. This dysregulation can contribute to the cancerous phenotype by affecting the overall epigenetic landscape of the tumor cells.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: HIST1H3B, histone cluster 1, H3j, H3, H3h, H3g, H3f1, H3e, H3d, H3c, H3b, H3a, H2ad; histone cluster 2, H3a, H3c, H3d
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:145  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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