Database Query Results : , , IDO

IDO, indoleamine 2,3-dioxygenase: Click to Expand ⟱
Source: HalifaxProj(inhibit)
Type:
An enzyme that plays a significant role in the metabolism of the amino acid tryptophan. It is involved in the kynurenine pathway, which leads to the production of several metabolites that can influence immune responses and have implications in cancer.
IDO has garnered attention for its role in immune evasion. Many tumors express IDO, which can lead to local depletion of tryptophan and accumulation of kynurenine and other metabolites. This can suppress T-cell activity and promote the differentiation of regulatory T cells, thereby helping tumors evade the immune system.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: IDO, indoleamine 2,3-dioxygenase
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:154  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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